Not only the effectiveness of bariatric surgery can vary with procedure, but also the outcomes of bariatric surgery vary between populations from different geographical regions. However, a recent RCT showed that GB is a superior procedure regarding weight loss and diabetes remission. Moreover, two randomized clinical trials (RCTs) comparing SG with RYGB reported that these surgeries did not differ in terms of EWL%. Conversely, another study showed a higher EWL% in GB patients, while no significant difference was found regarding T2DM remission. The first meta-analysis in this area showed that SG and gastric bypass (GB) were not significantly different regarding excess weight loss (EWL%) 18 months after surgery, whereas the resolution of T2DM was better in GB. The results of meta-analyses comparing SG with RYGB are controversial. According to recent estimates, sleeve gastrectomy (SG) is currently the most common procedure around the world (46% of all bariatric procedures), followed by Roux-en-Y gastric bypass (RYGB) (40% of all procedures). Although bariatric surgery has been performed extensively for several decades around the world, there is no consensus with regard to the safety and efficacy of different procedures. However, since SG was associated with a lower rate of complications, it seems that SG should be considered as a suitable procedure for obese patients, especially those with a healthier metabolic profile.Įvidence shows that bariatric surgery is more effective than conventional therapy for the control of obesity and its associated comorbidities. Conclusionīoth surgical procedures were effective in the control of obesity and remission of its comorbidities. The surgery duration, early complication rate, and nutritional deficiencies were lower in the SG group, compared to the GB group. Moreover, both procedures caused substantial improvements in various domains of quality of life. 54.7%) and the remission rate of dyslipidemia in all follow-ups were lower in the SG group, compared to the GB group. Conversely, the remission rate of hypertension in the 24-month follow-up (39.1% vs. Following the propensity score-adjusted analysis, the T2DM remission rate was not significantly different between the groups. Type 2 diabetes mellitus (T2DM) remission rate at the end of follow-up was 53.3% and 63.8% in the SG and GB groups, respectively. Effective outcomes were reported in both groups regarding the body composition indices. The prospectively collected data of patients, who presented to a specialized bariatric center and underwent a primary bariatric procedure, were compared in terms of weight loss, remission of obesity-associated comorbidities, complication rate, and quality of life improvement at 6-, 12-, and 24-month follow-ups. This is the first comprehensive report of a prospective cohort study, comparing sleeve gastrectomy (SG) with gastric bypass (GB) regarding their effectiveness and safety. Bariatric surgery is an effective treatment for obesity and its associated comorbidities.
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